Mycelium growing across a natural substrate

From microbes to fabrics

SynMetabio Biotechnology Co., Ltd. is a cutting-edge synthetic biology enterprise. We focus on material innovation driven by synthetic biology. Using natural substances including corn cobs, straw, coffee grounds, distiller's lees and oil as nutrients, we cultivate a new generation of innovative biomaterials.

SynMetabio scaled fermentation and production facility

Scaled Production Line

SynMetabio operates a large-scale production facility equipped with four 20-ton fermentation tanks and a 150-meter automated production line. With an annual output of 16 million meters of bio-based synthetic leather, we are well-positioned to meet the growing global demand for sustainable materials.

ANTAZERO X KRIS VAN ASSCHE安踏和Kris Van Assche合作系列

In September 2025, Anta officially announced its collaboration with internationally renowned fashion designer Kris Van Assche and launched the inaugural ANTAZERO X KRIS VAN ASSCHE collection. When sportswear fashion meets bio-based leather: ANTAZERO X Kris Van Assche unveils a new sustainable collection, positioning itself within sustainable sportswear fashion.

ANTAZERO collection made with Mulkol mycelium leather

Create 'Ath-Elegant' Pieces for
the Modern Wardrobe

The mycelium leather featured in the ANTAZERO x Kris Van Assche collection represents a true game-changer for sustainable fashion. Grown from agricultural waste and fermented bio-fibers, this carbon-negative, animal-friendly material delivers high-performance, luxurious alternatives for vegan leather parkas, footwear, and accessories.

SynMetabio closed-loop microalgae production system

Carbon-Negative Closed Loop,
Green Recycling

SynMetabio's closed-loop production system delivers a carbon-negative footprint, achieving lifecycle greenhouse gas emissions of -17.1659 kg CO₂ per kilogram of mycelium. Using only agricultural waste as feedstock and eliminating heavy metals, the process converts spent culture medium into liquid fertilizer via microalgae purification—resulting in zero wastewater, zero solid waste, and a fully sustainable ecological cycle.

Brown Mulkol bag with a branded material tag

Interior finished with decorative biomaterial surfaces

Technological Route

Strain screening

Special fungal strains with strong robustness are selected from nature, capable of adapting to extreme environments and significantly reducing sterilization and cooling costs in downstream production. The screening process targets efficient conversion of biomass (such as corn cobs, straw, and coffee grounds), prioritizing strains with fast growth rates and stable metabolic pathways.

Gene editing

We employ gene editing to endow the selected strains with traits that are better suited for industrial production and rapid growth.

Fermentation of biological materials

In our 20-ton fermentation tanks, the cultivated "seed liquid" is inoculated into the tank, where sufficient dissolved oxygen is ensured through agitation and the introduction of sterile air, while temperature and pH are precisely controlled. Under these conditions, the mycelium proliferates rapidly within just a few days. At the heart of this entire process lies the engineering of an optimal "reproduction factory" for the microbes, enabling the efficient mass production of their biomass.

Mass production

The biomaterials derived from fermentation are formulated into a specialized "slurry" that is fully compatible with existing artificial leather production lines. Large-scale manufacturing is then conducted on a 150-meter coating line, seamlessly integrating with established artificial leather processes and enabling rapid mass production.

Microalgae system

A microalgae circulation system is employed to treat production wastewater while releasing oxygen and absorbing carbon dioxide. This enables the entire production cycle to achieve "carbon-negative" status.